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(1)the design and operation of animal model for detecting andevaluating the activity of compounds, and (2) determinationof the dosage, toxicity, mode of action, metabolism, and fateof a drug candidate in the body. cialis on sale however, figure 5-15 shows the re-sults of a multiple-dose study in which the enteric-coated tabletand the film-coated tablet were administered four times a day,immediately after meals. 47in alcohol. 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